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Telomeres serve as caps at the ends of linear chromosomes. Which of the following is not true regarding the replication of telomeric sequences?
A) The lagging-strand telomeres are not completely replicated by DNA polymerase.
B) Telomeres are made of repeating sequences.
C) Additional repeated sequences are added to the template strand.
D) The leading strand doubles back on itself to form a primer for the lagging strand.

Answer :

Answer:

D) The leading strand doubles back on itself to form a primer for the lagging strand.

Explanation:

Telomeres are the end sequences of the linear cromosomes of DNA, and are formed by tandem repeats of simple DNA sequences. Because DNA polimerases can only extend the primers in the 5' to 3' direction, they can not copy the 5' ends of the linear molecules of DNA. A reverse transcriptase called telomerase is needed to replicate the telomeres.

This telomerase carries its own RNA template, which is complementary to the repeated sequences in the telomeres, as part of the enzymatic complex. The loose end of telomeric DNA binds to the ARN in telomerase, which will then function as a template for the extension of the template conductor strand in another unity of repetition. The lagging strand can be synthesized as a conventional initiation of RNA and polimerase activity.

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