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The enzyme carbonic anhydrase has zinc in a tetrahedral complex at its active site. Suggest a structural reason why car- bonic anhydrase synthesized with Ni2, Fe2, or Mn2 in place of Zn2 gives an enzyme with less catalytic efficiency​

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Suggest a structural reason why carbonic anhydrase synthesized with Ni2+, Fe2+, or Mn2+ in place of Zn2+ gives an enzyme with less catalytic efficiency.

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